| Date | Home | Away | Kick-off |
|---|
| 14th July, 2018 | Ayr United | Morton | 3:00pm |
| 21st July, 2018 | Albion Rovers | Ayr United | 3:00pm |
| 24th July, 2018 | Ayr United | Stenhousemuir | 7:45pm |
| 28th July, 2018 | Partick Thistle | Ayr United | 3:00pm |
| 4th August, 2018 | Ayr United | Partick Thistle | 3:00 pm |
| 11th August, 2018 | Inverness Caledonian Thistle | Ayr United | 3:00pm |
| 14th August, 2018 | Queens Park | Ayr United | 7:45pm |
| 25th August, 2018 | Ayr United | Dunfermline Athletic | 3:00pm |
| 1st September, 2018 | Queen of the South | Ayr United | 3:00pm |
| 15th September, 2018 | Ayr United | Falkirk | 15:00pm |
| 22nd September, 2018 | Alloa Athletic | Ayr United | 3:00pm |
| 29th September, 2018 | Morton | Ayr United | 3:00pm |
| 6th October, 2018 | Ayr United | Dundee United | 3:00pm |
| 20th October, 2018 | Ross County | Ayr United | 3:00pm |
| 27th October, 2018 | Partick Thistle | Ayr United | 3:00pm |
| 30th October, 2018 | Ayr United | Alloa Athletic | 7.45pm |
| 3rd November, 2018 | Falkirk | Ayr United | 3:00pm |
| 10th November, 2018 | Ayr United | Queen of the South | 3:00pm |
| 17th November, 2018 | Ayr United | Morton | 3:00pm |
| 1st December, 2018 | Dundee United | Ayr United | 3:00pm |
| 8th December, 2018 | Ayr United | Inverness Caledonian Thistle | 3:00pm |
| 15th December, 2018 | Ayr United | Ross County | 3:00pm |
| 22nd December, 2018 | Dunfermline Athletic | Ayr United | 3:00pm |
| 29th December, 2018 | Queen of the South | Ayr United | 3:00pm |
| 5th January, 2019 | Ayr United | Falkirk | 3:00pm |
| 12th January, 2019 | Inverness Caledonian Thistle | Ayr United | 3:00pm |
| 26th January, 2019 | Ayr United | Dundee United | 3:00pm |
| 2nd Ferbuary, 2019 | Alloa Athletic | Ayr United | 3:00pm |
| 16th February, 2019 | Morton | Ayr United | 3:00pm |
| 23rd February, 2019 | Ayr United | Dunfermline Athletic | 3:00pm |
| 26th February, 2019 | Ross County | Ayr United | 7:45pm |
| 2nd March , 2019 | Ayr United | Partick Thistle | 3:00pm |
| 9th March, 2019 | Falkirk | Ayr United | 3:00pm |
| 16th March, 2019 | Ayr United | Queen of the South | 3:00pm |
| 23rd March, 2019 | Ayr United | Morton | 3:00pm |
| 30th March, 2019 | Dunfermline Athletic | Ayr United | 3:00pm |
| 6th April, 2019 | Ayr United | Inverness Caledonian Thistle | 3:00pm |
| 13th April, 2019 | Dundee United | Ayr United | 3:00pm |
| 20th April, 2019 | Ayr United | Ross County | 3:00pm |
| 27th April, 2019 | Partick Thistle | Ayr United | 3:00pm |
| 4th May, 2019 | Ayr United | Alloa Athletic | 3:00pm |
